CARBAMAZEPINE SOLUBILITY ENHANCEMENT IN TANDEM WITH SWELLABLE POLYMER OSMOTIC PUMP TABLET: A PROMISING APPROACH FOR EXTENDED DELIVERY OF POORLY WATER-SOLUBLE DRUGS

Carbamazepine solubility enhancement in tandem with swellable polymer osmotic pump tablet: A promising approach for extended delivery of poorly water-soluble drugs

Elementary osmotic pump (EOP) is a unique extended release (ER) drug delivery system based on the principle of osmosis.It has the ability Ceramic Ornament Gift Box to minimize the amount of the drug, accumulation and fluctuation in drug level during chronic uses.Carbamazepine (CBZ), a poorly water-soluble antiepileptic drug, has serious side effect

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Isolated adrenocorticotropic hormone deficiency associated with sintilimab therapy in a patient with advanced lung adenocarcinoma: a case report and literature review

Abstract Background Several immune checkpoint inhibitors have been implemented for cancer treatment which have shown some degree of antitumor effcacy, while immune-related adverse events (irAEs) that affect multiple organ functions ensue which obviously should not be neglected.Though less common than other kinds of irAEs, Immune checkpoint inhibito

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Membrane Nanotubes between peritoneal mesothelial cells: functional connectivity and crucial participation during inflammatory reactions

Peritoneal dialysis (PD) has attained increased relevance as continuous renal replacement therapy over the past years.During this treatment, the peritoneum functions as dialysis membrane to eliminate diffusible waste products from the blood-stream.Success and efficacy of this treatment is dependent on the integrity of the peritoneal membrane.Chroni

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EXAMPLE OF GRAGUAL TRANSFORMATION OF STIFFNESS MATRIX AND MAIN SET OF EQUATIONS AT ADDITIONAL FINITE ELEMENT METHOD

The paper considers the example of gradual transformation of the stiffness matrix and the main set of equations at Additional top Finite Element Method (AFEM).It is corresponded to the increase of load and the ideal failure model of structure.AFEM uses the additional design diagrams and additional finite elements (AFE) for this operation.This proce

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EXAMPLE OF GRAGUAL TRANSFORMATION OF STIFFNESS MATRIX AND MAIN SET OF EQUATIONS AT ADDITIONAL FINITE ELEMENT METHOD

The paper considers the example of gradual transformation of the stiffness matrix and the main set of equations at Additional top Finite Element Method (AFEM).It is corresponded to the increase of load and the ideal failure model of structure.AFEM uses the additional design diagrams and additional finite elements (AFE) for this operation.This proce

read more